Which sign is typically associated with impending labor?

The loss of the mucus plug is a sign commonly associated with impending labor. The mucus plug is a thick gel-like substance that accumulates in the cervical canal during pregnancy, serving as a protective barrier against bacteria and infections. As labor approaches, hormonal changes lead to the softening and dilation of the cervix, which can result in the expulsion of the mucus plug. This event, often described as a "bloody show," may contain blood streaks and is an indication that the body is preparing for labor.

In contrast, weight gain, increased appetite, and indigestion do not signify the onset of labor and may occur at any stage during pregnancy. Weight gain is generally expected as the pregnancy progresses, while increased appetite can occur at various points due to metabolic changes. Indigestion is a common discomfort experienced during pregnancy, particularly in the later stages, but it does not directly indicate that labor is imminent. Understanding these signs helps expectant parents recognize the appropriate time to seek medical assistance.